Adaptive immune system and vaccination responses in Down syndrome.

PROEFSCHRIFT: Kusters MAA. Thesis. Leiden University, 2014. Promotores prof. dr. J.T. van Dissel, prof. dr. E. de Vries. ISBN 978-90-9027849-0.

Epidemiology of respiratory symptoms in children with Down syndrome: a nationwide prospective web-based parent-reported study.

ARTIKEL: Verstegen RH, van Hout RW, de Vries E. BMC Pediatr. 2014 Apr 15;14(1):103.

Impact of Down syndrome on the performance of neonatal screening assays for severe primary immunodeficiency diseases.

ARTIKEL: Verstegen RH, Borte S, Bok LA, van Zwieten PH, von Döbeln U, Hammarström L, de Vries E. J Allergy Clin Immunol. 2014 Apr;133(4):1208-11.

Defective B-cell memory in patients with Down syndrome.

ARTIKEL: Verstegen RHJ, Driessen GJ, Bartol SJW, van der Burg M, de Vries E, van Zelm MC. J Allergy Clin Immunol. 2014 Aug 23.

Functionality of the pneumococcal antibody response in Down syndrome subjects.

ARTIKEL: Kusters MAA, Manders NCC, de Jong BAW, van Hout RWNM,RijkersGT, de Vries E. Vaccine. 2013 Dec 16;31(52):6261-5.

Significant impact of recurrent respiratory tract infections in children with Down syndrome.

ARTIKEL: Verstegen RH, van Gameren-Oosterom HB, Fekkes M, Dusseldorp E, de Vries E, van Wouwe JP. Child Care Health Dev. 2012 Jul 9.

Increased Circulating Apoptotic Lymphocytes in Children with Down Syndrome.

ARTIKEL: Gemen EFA, Verstegen RHJ, Leuvenink J, de Vries E. Pediatr Blood Cancer 2012 Dec 15;59(7):1310-2.

Influenza A/H1N1 vaccination respons is inadequate in Down syndrome children when the latest latest cut-off values are used.

ARTIKEL: Kusters MA, Bok LA, Bolz WEA, Huijskens EGW, Peeters MF, de Vries E. Pediatr Infect Dis J. 2012 Dec;31(12):1284-5.

Incidence of respiratory symptoms in children with Down syndrome: feasibility of a web-based parent-reported prospective study.

POSTER: Verstegen RHJ, de Vries E. European Society for Paediatric Infectious Diseases, Milan, Italy, 2013.

Adequate polysaccharide antibody responses despite B-lymphocytopenia in Down syndrome children.

POSTER: Kusters MAA, Manders N, de Jong B, Rijkers GT, de Vries E. European Society for Immunodeficiencies ESID, Florence, Italy, 2012.

Down syndrome: is it really characterized by precocious immunosenescence?

ARTIKEL: Kusters MA, Verstegen RH, de Vries E. Aging Dis. 2011 Dec;2(6):538-45.

Decreased response after conjugated meningococcal serogroup C vaccination in children with down syndrome.

ARTIKEL: Kusters MA, Jol-Van Der Zijde EC, Gijsbers RH, de Vries E. Pediatr Infect Dis J. 2011 Sep;30(9):818-9.

Impact of respiratory tract infections in children with Down syndrome.

POSTER: Verstegen RHJ, van Gameren-Oosterom HBM, Fekkes M, Dusseldorp EML, de Vries E, van Wouwe JP. European Society for Paediatric Infectious Diseases, Den Haag, Nederland, 2011.

Prevention of recurrent respiratory tract infections in Down syndrome: what could potentially be gained?

POSTER: Verstegen RHJ,van Gameren-Oosterom HBM, Fekkes M, Dusseldorp E, de Vries E, van Wouwe JP. European Society for Social Pediatrics and Child Health, Maastricht, Nederland, 2011.

Impact of respiratory tract infections on developmental skils in children with Down syndrome.

POSTER: Verstegen RHJ, van Gameren-Oosterom HBM, Fekkes M, Dusseldorp E, de Vries E, van Wouwe JP. Impact of respiratory tract infections on developmental skils in children with Down syndrome. European Society for Paediatric Research, Newcastle, UK, 2011.

Protective but lower levels of antibodies after single conjugated meningococcal serogroup C vaccination in children with Down syndrome.

POSTER: Kusters MA, Jol-van der Zijde CM, Gijsbers R, de Vries E. European Society for Paediatric Infectious Diseases, Den Haag, Nederland, 2011.

Children with Down syndrome show decreased antibody response to tetanus toxoid.

POSTER: Kusters MAA, Jol-van der Zijde CM, van Tol MJD, Bolz WEA, Bok LA, Visser M, de Vries E. European Congress of Immunology, Berlin, Germany, 2009.

Serum antibody response to tetanus toxoid in children with Down syndrome.

POSTER: Kusters MAA, Jol-van der Zijde CM, van Tol MJD, Bolz WEA, Bok LA, Visser M, de Vries E. European Society for Paediatric Infectious Diseases, Brussel, Belgium, 2009.

Impaired avidity maturation after tetanus toxoid booster in children with Down syndrome.

ARTIKEL: Kusters MA, Jol-van der Zijde CM, van Tol MJ, Bolz WE, Bok LA, Visser M, de Vries E. Pediatr Infect Dis J, 2011 Apr;30(4):357-9.

Both normal memory counts and decreased naive cells favor intrinsic defect over early senescence of Down syndrome T lymphocytes.

ARTIKEL: Kusters MA, Gemen EF, Verstegen RH, Wever PC, de Vries E. Pediatr Res. 2010 May;67(5):557-62.