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Adaptive immune system and vaccination responses in Down syndrome.

PROEFSCHRIFT: Kusters MAA. Thesis. Leiden University, 2014. Promotores prof. dr. J.T. van Dissel, prof. dr. E. de Vries. ISBN 978-90-9027849-0.

Defective B-cell memory in patients with Down syndrome.

ARTIKEL: Verstegen RHJ, Driessen GJ, Bartol SJW, van der Burg M, de Vries E, van Zelm MC. J Allergy Clin Immunol. 2014 Aug 23.

Functionality of the pneumococcal antibody response in Down syndrome subjects.

ARTIKEL: Kusters MAA, Manders NCC, de Jong BAW, van Hout RWNM,RijkersGT, de Vries E. Vaccine. 2013 Dec 16;31(52):6261-5.

Increased Circulating Apoptotic Lymphocytes in Children with Down Syndrome.

ARTIKEL: Gemen EFA, Verstegen RHJ, Leuvenink J, de Vries E. Pediatr Blood Cancer 2012 Dec 15;59(7):1310-2.

Influenza A/H1N1 vaccination respons is inadequate in Down syndrome children when the latest latest cut-off values are used.

ARTIKEL: Kusters MA, Bok LA, Bolz WEA, Huijskens EGW, Peeters MF, de Vries E. Pediatr Infect Dis J. 2012 Dec;31(12):1284-5.

Adequate polysaccharide antibody responses despite B-lymphocytopenia in Down syndrome children.

POSTER: Kusters MAA, Manders N, de Jong B, Rijkers GT, de Vries E. European Society for Immunodeficiencies ESID, Florence, Italy, 2012.

Down syndrome: is it really characterized by precocious immunosenescence?

ARTIKEL: Kusters MA, Verstegen RH, de Vries E. Aging Dis. 2011 Dec;2(6):538-45.

Decreased response after conjugated meningococcal serogroup C vaccination in children with down syndrome.

ARTIKEL: Kusters MA, Jol-Van Der Zijde EC, Gijsbers RH, de Vries E. Pediatr Infect Dis J. 2011 Sep;30(9):818-9.

Protective but lower levels of antibodies after single conjugated meningococcal serogroup C vaccination in children with Down syndrome.

POSTER: Kusters MA, Jol-van der Zijde CM, Gijsbers R, de Vries E. European Society for Paediatric Infectious Diseases, Den Haag, Nederland, 2011.

Serum antibody response to tetanus toxoid in children with Down syndrome.

POSTER: Kusters MAA, Jol-van der Zijde CM, van Tol MJD, Bolz WEA, Bok LA, Visser M, de Vries E. European Society for Paediatric Infectious Diseases, Brussel, Belgium, 2009.

Impaired avidity maturation after tetanus toxoid booster in children with Down syndrome.

ARTIKEL: Kusters MA, Jol-van der Zijde CM, van Tol MJ, Bolz WE, Bok LA, Visser M, de Vries E. Pediatr Infect Dis J, 2011 Apr;30(4):357-9.

Both normal memory counts and decreased naive cells favor intrinsic defect over early senescence of Down syndrome T lymphocytes.

ARTIKEL: Kusters MA, Gemen EF, Verstegen RH, Wever PC, de Vries E. Pediatr Res. 2010 May;67(5):557-62.

Down syndrome B-lymphocyte subpopulations, intrinsic defect or decreased T-lymphocyte help.

ARTIKEL: Verstegen RH, Kusters MA, Gemen EF, de Vries E. Pediatr Res. 2010 May;67(5):563-9.

Intrinsic defect of the immune system in children with Down syndrome: a review.

ARTIKEL: Kusters MA, Verstegen RH, Gemen EF, de Vries E. Clin Exp Immunol. 2009 May;156(2):189-93.